Abiogenesis, the process of life emerging from non-living matter, is one of the most profound and challenging questions in science. It represents the transition from the realm of chemistry to the emergence of biology, a pivotal moment in the history of our universe. Despite its immense significance, abiogenesis remains shrouded in mystery, with scientists continuously exploring various hypotheses and conducting experiments to unravel the enigma of how life first arose on Earth billions of years ago.

The study of abiogenesis is a multidisciplinary endeavor, drawing upon knowledge from fields such as chemistry, geology, astronomy, and biology. It seeks to understand the conditions that existed on the early Earth and how these conditions could have facilitated the spontaneous formation of the first self-replicating molecules, the precursors to life as we know it. Researchers investigate the potential pathways that may have led to the synthesis of complex organic compounds, the assembly of these compounds into larger structures, and the eventual emergence of primitive cellular systems capable of replication and evolution.


Stuart Kauffman   (1996)

At Home in the Universe

The Search for the Laws of Self-Organization and Complexity

Stuart Kauffman’s At Home in the Universe unveils a scientific revolution centered on spontaneous order in complex systems. Kauffman argues that complexity itself triggers self-organization, revealing life as a natural outcome rather than a chance event. From cell development to cultural evolution, he explores how this principle shapes diverse phenomena. Praised as a visionary by Stephen Jay Gould and Philip Anderson, Kauffman’s work extends Darwin’s theory and offers profound insights into the essence of life.

Carl Sagan and Ann Druyan   (1980)

One Voice in the Cosmic Fugue

Cosmos, Episode 2

Sagan discusses the story of the Heike crab and artificial selection of crabs resembling samurai warriors, as an opening into a larger discussion of evolution through natural selection (and the pitfalls of intelligent design). Among the topics are the development of life on the Cosmic Calendar and the Cambrian explosion; the function of DNA in growth; genetic replication, repairs, and mutation; the common biochemistry of terrestrial organisms; the creation of the molecules of life in the Miller-Urey experiment; and speculation on alien life (such as life in Jupiter's clouds). In the Cosmos Update ten years later, Sagan remarks on RNA also controlling chemical reactions and reproducing itself and the different roles of comets (potentially carrying organic molecules or causing the Cretaceous–Paleogene extinction event).

Stuart Kauffman   (2024)

Is the Emergence of Life an Expected Phase Transition in the Evolving Universe?

This article proposes a new definition of life as chemical systems that achieve catalytic closure, constraint closure, and spatial closure. It argues that the emergence of such living systems is an expected phase transition in the evolving universe. However, the ever-creative evolution of life thereafter cannot be explained by physics alone, showing the limits of reductionism. Life is a double miracle—expected yet unexplainable.