Portrait of Michael Jacob

Michael Jacob

Dr. Michael Jacob is an American psychiatrist, neuroscientist, and interdisciplinary theorist whose work explores one of the most challenging questions in science: how the physical processes of the brain give rise to thought, perception, and mental illness. As an Assistant Professor of Psychiatry at the University of California, San Francisco and a researcher with the San Francisco VA Health Care System, Jacob combines clinical psychiatry with advanced brain-imaging techniques such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI). His research focuses particularly on schizophrenia and the relationship between neural activity, blood flow, and metabolism in the brain, with the goal of identifying new biological markers that could improve diagnosis and treatment.

Beyond his clinical neuroscience research, Jacob is known for pursuing unusually broad and integrative ideas that connect biology, cognition, information, and complex systems. His publications have examined topics ranging from brain dynamics and psychiatric disorders to the role of energy and information in living organisms, and even the possibility of understanding humanity itself as a planetary-scale living system. Drawing on influences from neuroscience, evolutionary theory, anthropology, and philosophy, he argues that mind and cognition cannot be fully understood in isolation from the metabolic and ecological processes that sustain them. This combination of rigorous experimental work and wide-ranging theoretical inquiry has made Jacob a distinctive voice among contemporary researchers seeking to bridge the gap between the biological sciences and the study of consciousness, behavior, and human society.

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Francis Heylighen, Shima Beigi and Clément Vidal

The Third Story of the Universe

Religion said “God did it.” Science said “physics did it—deal with it.” Neither told you why to get out of bed. The Third Story says the universe has been self-organizing toward consciousness since the Big Bang, and you’re a neuron in a waking planetary brain. Your purpose? More synergy, less friction. The cosmos is becoming. Join in.